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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP5 All Species: 20.3
Human Site: S1166 Identified Species: 44.67
UniProt: Q13017 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13017 NP_001025226.1 1502 172460 S1166 T L F S K A K S Y Y R R T H S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115141 1502 172349 S1166 T L F S K A K S Y Y R R T H S
Dog Lupus familis XP_850368 1503 172366 S1167 T L F S K A K S Y Y R R T H S
Cat Felis silvestris
Mouse Mus musculus P97393 1501 171908 H1165 L C L V K P S H T T E E H T Q
Rat Rattus norvegicus P81128 1513 172361 T1160 S K P V L Y R T R C T R L G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512048 1500 171507 S1163 T L F S K A K S Y Y R R T H S
Chicken Gallus gallus XP_426439 1505 172078 S1168 T L F S K A K S Y Y R R T H S
Frog Xenopus laevis NP_001084674 1477 168747 C1155 P V L Y R T K C A K L G K F S
Zebra Danio Brachydanio rerio XP_001336016 1502 171923 A1165 I L F S K T K A Y H R R V H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX32 1561 178754 R1152 P V D K D G K R Y D H A Q L D
Honey Bee Apis mellifera XP_624122 1551 176949 S1153 S D S D S E W S S L E R Q R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 98.3 N.A. 93.6 51.1 N.A. 93.2 91.3 49.2 73.9 N.A. 26.3 29.5 N.A. N.A.
Protein Similarity: 100 N.A. 99.8 99 N.A. 95.1 69.8 N.A. 96.7 95.6 68.3 85.9 N.A. 49 50.4 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 6.6 6.6 N.A. 100 100 13.3 66.6 N.A. 13.3 13.3 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 6.6 26.6 N.A. 100 100 26.6 80 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 46 0 10 10 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % C
% Asp: 0 10 10 10 10 0 0 0 0 10 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 19 10 0 0 0 % E
% Phe: 0 0 55 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 0 0 0 10 0 10 10 0 10 55 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 10 0 10 64 0 73 0 0 10 0 0 10 0 0 % K
% Leu: 10 55 19 0 10 0 0 0 0 10 10 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 10 % Q
% Arg: 0 0 0 0 10 0 10 10 10 0 55 73 0 10 10 % R
% Ser: 19 0 10 55 10 0 10 55 10 0 0 0 0 0 64 % S
% Thr: 46 0 0 0 0 19 0 10 10 10 10 0 46 10 0 % T
% Val: 0 19 0 19 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 10 0 0 64 46 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _